Reading up on AlphaFold

Specialization is inevitable across optimization, biology, markets, and ML because fit beats breadth under finite resource constraints.

Scientific discovery emerges from a loop of human question-posing, LLM proposal, external verification, and human curation, not from AI alone.

Demis Hassabis estimates Google DeepMind is 75% of the way to achieving artificial general intelligence, citing AlphaFold and other breakthroughs.

A software developer finds greater happiness coaching youth basketball than in his tech career, prompting reflection on meaning and purpose beyond code.

The article outlines potential downsides and limitations of AI development, including model stagnation, chip shortages, and cheap models, while also predicting advances like robot models and continual learning.

AGI capable of most cognitive work could arrive by 2028–2034, but deployment will lag capability due to verification bottlenecks, uneven automation, and institutional friction.

The documentary 'The Thinking Game' profiles Google DeepMind and Demis Hassabis, focusing on the AlphaFold breakthrough and the pursuit of artificial general intelligence.